Job Description

Research Scientist Opportunity

We are currently seeking a Research Scientist to provide support services to satisfy the overall operational objectives within the National Institutes of Health. This is a full-time, on-site opportunity in Bethesda, MD.

What You Will Do:

• Continuously optimize and implement protocols to enhance the differentiation of human induced pluripotent stem cells (iPSCs) into engraftable hematopoietic stem cells (HSCs).
• Conduct experiments to ectopically activate master transcription factors that are crucial for directing cell lineage determination, ensuring that the iPSCs differentiate into the desired cell type.
• Investigate and apply inhibitors of key epigenetic regulators during the early stages of differentiation to enhance the developmental pathway towards HSCs.
• Optimize the ectopic expression of homing receptors, with a focus on the CXCR4 chemokine receptor, to improve the homing efficiency and survival of HSCs post-transplantation.
• Analyze experimental data, maintain detailed records of experiments, and prepare reports or presentations summarizing findings and progress in refining the differentiation platform.
• Work collaboratively with other researchers and team members to integrate findings and refine strategies, ensuring alignment with overall research goals.
• Contribute to the identification of learning needs for the CMTB environment and provide learning opportunities for others.
• Recommend and implement approaches and solutions to problems that may arise.
• Collaborate with experts to analyze and report data as applicable.
• Draft manuscripts for publication in scientific journals.
• Present findings at scientific meetings.

What You Will Need:

• Ph.D. and/or M.D.
• At least four (4) years of biology related research.
• Proficient in microbiology techniques, including media preparation, bacteria cultivation, and bioreactor setup.
• Experience in enzyme production for industrial applications, demonstrating expertise in bioprocess engineering.
• Expertise in quantitative and qualitative research and analytic methods.

What Would Be Nice To Have:

• Experience with tools such as SAS and R is preferred.
• Strong oral and written communication skills.
• Ability to work independently and as part of a team.
• Strong time management and organizational skills.

The annual salary range for this position is $85,000.00-$141,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.

What We Offer:

• Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
• Benefits include: Medical, Rx, Dental & Vision Insurance, Personal and Family Sick Time & Company Paid Holidays, Parental Leave, 401(k) Retirement Plan, Group Term Life and Travel Assistance, Voluntary Life and AD&D Insurance, Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts, Transit and Parking Commuter Benefits, Short-Term & Long-Term Disability, Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities, Employee Referral Program, Corporate Sponsored Events & Community Outreach, Care.com annual membership, Employee Assistance Program, Supplemental Benefits via Corestream, Position may be eligible for a discretionary variable incentive bonus.

About Guidehouse:

Guidehouse is an Equal Opportunity EmployerProtected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation. Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco. If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at RecruitingAccommodation@guidehouse.com.

All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation. All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or guidehouse@myworkday.com. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process. If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse's Ethics Hotline. If you want to check the validity of correspondence you have received, please contact recruiting@guidehouse.com. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant's dealings with unauthorized third parties. Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.

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